Can aspirin prevent DVT in high-risk flyers?

Nicky, a 48-year-old business executive, asked me for advice about deep vein thrombosis (DVT) prophylaxis prior to travel to the US.

She was a carrier for factor V Leiden. She had used enoxaparin (Clexane) in the past, but recently read about aspirin on the internet. Is this a reasonable choice?

CLINICAL QUESTION