The drugs that have cancer on the run

Checkpoint inhibitors offer another approach for tackling advanced melanoma
A CTLA-4 protein. CTLA4-blocking antibodies are used in cancer therapy (immune checkpoint blockade therapy). Photo: Alamy
A CTLA-4 protein. CTLA4-blocking antibodies are used in cancer therapy (immune checkpoint blockade therapy). Photo: Alamy

Attempts to improve the survival of patients with advanced or metastatic melanoma have, until recently, proven futile.